In Vivo Phosphoproteomics Analysis Reveals the Cardiac Targets of β-Adrenergic Receptor Signaling

Alicia Lundby; Martin N. Andersen; Annette B. Steffensen; Heiko Horn; Christian D. Kelstrup; Chiara Francavilla; Lars J. Jensen; Nicole Schmitt; Morten B. Thomsen; Jesper V. Olsen

doi:10.1126/scisignal.2003506

Research ResourceBiochemistry

In Vivo Phosphoproteomics Analysis Reveals the Cardiac Targets of β-Adrenergic Receptor Signaling

Alicia Lundby¹,²,³,*,
Martin N. Andersen³,
Annette B. Steffensen³,
Heiko Horn¹,
Christian D. Kelstrup¹,
Chiara Francavilla¹,
Lars J. Jensen¹,
Nicole Schmitt³,
Morten B. Thomsen³, and
Jesper V. Olsen¹,*

¹Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3b, DK-2200 Copenhagen, Denmark.
²The Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
³The Danish National Research Foundation Centre for Cardiac Arrhythmia, DK-2200 Copenhagen N, Denmark.

↵*Corresponding author. E-mail: alicia.lundby{at}cpr.ku.dk (A.L.); jesper.olsen{at}cpr.ku.dk (J.V.O.)

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Science Signaling 04 Jun 2013:
Vol. 6, Issue 278, pp. rs11
DOI: 10.1126/scisignal.2003506

Alicia Lundby

1Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3b, DK-2200 Copenhagen, Denmark.

2The Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.

3The Danish National Research Foundation Centre for Cardiac Arrhythmia, DK-2200 Copenhagen N, Denmark.

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For correspondence: alicia.lundby@cpr.ku.dk jesper.olsen@cpr.ku.dk

Martin N. Andersen

3The Danish National Research Foundation Centre for Cardiac Arrhythmia, DK-2200 Copenhagen N, Denmark.

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Annette B. Steffensen

3The Danish National Research Foundation Centre for Cardiac Arrhythmia, DK-2200 Copenhagen N, Denmark.

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Heiko Horn

1Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3b, DK-2200 Copenhagen, Denmark.

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Christian D. Kelstrup

1Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3b, DK-2200 Copenhagen, Denmark.

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Chiara Francavilla

1Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3b, DK-2200 Copenhagen, Denmark.

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Lars J. Jensen

1Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3b, DK-2200 Copenhagen, Denmark.

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Nicole Schmitt

3The Danish National Research Foundation Centre for Cardiac Arrhythmia, DK-2200 Copenhagen N, Denmark.

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Morten B. Thomsen

3The Danish National Research Foundation Centre for Cardiac Arrhythmia, DK-2200 Copenhagen N, Denmark.

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Jesper V. Olsen

1Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3b, DK-2200 Copenhagen, Denmark.

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For correspondence: alicia.lundby@cpr.ku.dk jesper.olsen@cpr.ku.dk

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In Vivo Phosphoproteomics Analysis Reveals the Cardiac Targets of β-Adrenergic Receptor Signaling

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