Contents
Vol 6, Issue 280
Contents
Research Articles
- bHLH Transcription Factors That Facilitate K+ Uptake During Stomatal Opening Are Repressed by Abscisic Acid Through Phosphorylation
Decreasing the transcription of genes encoding K+ channels contributes to inhibition of stomatal opening in Arabidopsis.
- Inhibition of TGF-β Signaling at the Nuclear Envelope: Characterization of Interactions Between MAN1, Smad2 and Smad3, and PPM1A
MAN1 at the nuclear envelope may block TGF-β signaling by stimulating dephosphorylation of the Smad transcription factors.
Perspective
- Ubiquitin System: Direct Effects Join the Signaling
By sterically altering protein-protein interactions, ubiquitin modification can directly affect protein function.
Editors' Choice
- Coordinating Neuronal Development
Brain stem neurons direct the specification of their spinal cord targets, the motor neurons.
- Too Much or Too Little
Different concentrations of carbon dioxide activate distinct projection neurons and, hence, elicit different responses.
- PKA Augments Hippo Signaling
Protein kinase A represses activity of the transcriptional coactivator YAP.
- Methylation and Methuselah?
Reduced protein methyltransferase activity improves progeria-like disease phenotypes.
- Specifying Substrate Specificity
Distinct intracellular signaling pathways acting on the substrates of a protease could determine which substrates are cleaved.
- Almost Open
Crystal structure analysis reveals that βγ subunits twist the GIRK2 K+ channel into a conformation closer to open.