10 December 2013
Vol 6, Issue 305

About The Cover

Cover image expansion

Online Cover This week features a Research Article that shows a mechanism by which muscle generation is inhibited during inflammation. The proinflammatory cytokine interferon-γ stimulates the recruitment of repressor proteins of the Jumonji and Polycomb families to the promoters of muscle-specific genes to repress myogenesis. The image is a colored transmission electron micrograph of muscle fibrils (brown) in the heart. [Image: Thomas Deerinck, NCMIR/Science Source]