As well as its role as an intracellular energy source, extracellular adenosine triphosphate (ATP) has diverse functions as a signaling molecule. ATP receptors have been identified in animal cells, but searches based on structural homology have not identified ATP receptors in plants.Choi et al. have now identified an ATP receptor in the model plant Arabidopsis thaliana by tracking down the cause of mutations that leave mutant plants unresponsive to ATP signals. The receptor identified carries an intracellular kinase domain and an extracellular lectin domain.
J. Choi, K. Tanaka, Y. Cao, Y. Qi, J. Qiu, Y. Liang, S. Y. Lee, G. Stacey, Identification of a plant receptor for extracellular ATP. Science 343, 290–294 (2014). [Abstract] [Full Text]
