Contents
Vol 7, Issue 311
Contents
Research Articles
- Interconnected Network Motifs Control Podocyte Morphology and Kidney Function
Integrated network analysis and dynamical modeling predict intervention strategies to reverse kidney damage.
- Noncanonical NF-κB Signaling Is Limited by Classical NF-κB Activity
Disrupting crosstalk between classical and noncanonical NF-κB signaling pathways may contribute to symptoms of immunodeficiency.
Podcast
- Science Signaling Podcast: 4 February 2014
Proteomic analysis and computational methods identify potential targets for reversing kidney damage.
Editors' Choice
- Cyclin C Moves Out of the Nucleus
The transcriptional repressor cyclin C leaves the nucleus to promote mitochondrial fission.
- Building a Heart with Cyclin
Cyclin and cyclin-dependent kinase activity play independent roles in the stimulation of the transcription factor GATA4.
- Coordinating the Clock
Flies use a mechanosensory organ to sense a low-frequency vibration and reset the brain’s biological clock.
- A Matter of Timing
A regulatory circuit controlling plant flowering genes leads the way to reconstruction of a time-delay control system.
- Activating mTOR with Ral Instead of Rheb
Lack of a key regulatory complex in worms leads to the identification of a previously unknown regulatory mechanism for mTOR in mammalian cells.
