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Research ArticleSystems Biology
Interconnected Network Motifs Control Podocyte Morphology and Kidney Function
- Evren U. Azeloglu1,*,
- Simon V. Hardy1,*,†,
- Narat John Eungdamrong1,‡,
- Yibang Chen1,
- Gomathi Jayaraman1,
- Peter Y. Chuang2,
- Wei Fang1,
- Huabao Xiong3,
- Susana R. Neves1,4,
- Mohit R. Jain5,
- Hong Li5,
- Avi Ma’ayan1,
- Ronald E. Gordon6,
- John Cijiang He1,2,§¶, and
- Ravi Iyengar1,4,§¶
- 1Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, NY 10029, USA.
- 2Division of Nephrology, Department of Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA.
- 3Immunobiology Center, Mount Sinai School of Medicine, New York, NY 10029, USA.
- 4Systems Biology Center New York, Mount Sinai School of Medicine, New York, NY 10029, USA.
- 5Department of Biochemistry and Molecular Biology, Center for Advanced Proteomics Research, University of Medicine and Dentistry of New Jersey–New Jersey Medical School Cancer Center, Newark, NJ 07103, USA.
- 6Department of Pathology, Mount Sinai School of Medicine, New York, NY 10029, USA.
- ↵¶Corresponding author. E-mail: ravi.iyengar{at}mssm.edu (R.I.); cijiang.he{at}mssm.edu (J.C.H.)
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↵* These authors contributed equally to this work (joint first authors).
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↵† Present address: Université Laval, 2325 Rue de l’Université, Québec, Québec G1V 0A6, Canada.
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↵‡ Present address: New York University Medical Center, New York, NY 10016, USA.
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↵§ These authors contributed equally to this work (joint senior authors).
See allHide authors and affiliations
Science Signaling 04 Feb 2014:
Vol. 7, Issue 311, pp. ra12
DOI: 10.1126/scisignal.2004621
Vol. 7, Issue 311, pp. ra12
DOI: 10.1126/scisignal.2004621
Evren U. Azeloglu
1Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, NY 10029, USA.
Simon V. Hardy
1Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, NY 10029, USA.
Narat John Eungdamrong
1Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, NY 10029, USA.
Yibang Chen
1Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, NY 10029, USA.
Gomathi Jayaraman
1Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, NY 10029, USA.
Peter Y. Chuang
2Division of Nephrology, Department of Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA.
Wei Fang
1Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, NY 10029, USA.
Huabao Xiong
3Immunobiology Center, Mount Sinai School of Medicine, New York, NY 10029, USA.
Susana R. Neves
1Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, NY 10029, USA.
4Systems Biology Center New York, Mount Sinai School of Medicine, New York, NY 10029, USA.
Mohit R. Jain
5Department of Biochemistry and Molecular Biology, Center for Advanced Proteomics Research, University of Medicine and Dentistry of New Jersey–New Jersey Medical School Cancer Center, Newark, NJ 07103, USA.
Hong Li
5Department of Biochemistry and Molecular Biology, Center for Advanced Proteomics Research, University of Medicine and Dentistry of New Jersey–New Jersey Medical School Cancer Center, Newark, NJ 07103, USA.
Avi Ma’ayan
1Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, NY 10029, USA.
Ronald E. Gordon
6Department of Pathology, Mount Sinai School of Medicine, New York, NY 10029, USA.
John Cijiang He
1Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, NY 10029, USA.
2Division of Nephrology, Department of Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA.
Ravi Iyengar
1Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, NY 10029, USA.
4Systems Biology Center New York, Mount Sinai School of Medicine, New York, NY 10029, USA.
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