Research ArticleCancer
β1 Integrin Inhibition Elicits a Prometastatic Switch Through the TGFβ–miR-200–ZEB Network in E-Cadherin–Positive Triple-Negative Breast Cancer
- Hoa H. Truong1,*,
- Jiangling Xiong1,*,
- Veerander P. S. Ghotra1,
- Ella Nirmala1,
- Lizette Haazen1,
- Sylvia E. Le Dévédec1,
- Hayri E. Balcioğlu1,
- Shuning He2,
- B. Ewa Snaar-Jagalska2,
- Erno Vreugdenhil3,
- John H. N. Meerman1,
- Bob van de Water1, and
- Erik H. J. Danen1,†
- 1Division of Toxicology, Leiden Academic Center for Drug Research, Leiden University, Leiden 2333CC, the Netherlands.
- 2Department of Molecular Cell Biology, Institute of Biology, Leiden University, Leiden 2333CC, the Netherlands.
- 3Division of Medical Pharmacology, Leiden Academic Center for Drug Research, Leiden University, Leiden 2333CC, the Netherlands.
- ↵†Corresponding author. E-mail: e.danen{at}lacdr.leidenuniv.nl
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Science Signaling 11 Feb 2014:
Vol. 7, Issue 312, pp. ra15
DOI: 10.1126/scisignal.2004751
