22 April 2014
Vol 7, Issue 322

About The Cover

Cover image expansion

Online Cover This week features a Research Article that suggests that the nuclear skeleton, in particular nuclear lamin-A, and the cytoplasmic skeleton, in particular F-actin, cooperate in T cell activation. The image shows an artist's rendition of how nuclear lamin-A proteins in the T cell (blue) might stabilize the F-actin network at the contact region with an antigen-presenting cell (orange). [Image: Val Altounian, Science Signaling]