Editors' ChoiceNeuroscience

Watching Brain Molecules

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Science Signaling  06 May 2014:
Vol. 7, Issue 324, pp. ec122
DOI: 10.1126/scisignal.2005441

Functional neuroimaging using magnetic resonance imaging (MRI) molecular sensors would be useful for mechanistic analysis of neural systems. Lee et al. applied MRI-detectable sensors to measure molecular aspects of brain function in conjunction with noninvasive imaging. The molecular sensor revealed a quantitative spatiotemporal map of dopamine release in the ventral striatum, a brain area involved in processing rewards.

T. Lee, L. X. Cai, V. S. Lelyveld, A. Hai, A. Jasanoff, Molecular-level functional magnetic resonance imaging of dopaminergic signaling. Science344, 533–535 (2014). [Abstract] [Full Text]

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