29 July 2014
Vol 7, Issue 336

About The Cover

Cover image expansion

Online Cover This week features a Research Article that shows how chemokines, proteins that act as tracking signals to lead lymphocytes to sites of infection, enhance the cell surface expression of integrins, proteins that mediate lymphocyte adhesion and migration. Mice deficient in a factor that mediates chemokine-dependent integrin presentation showed defective trafficking of lymphocytes to lymphoid organs. The image highlights the lymphatic system (green) through which lymphocytes traffic. [Image: Getty Images/iStockphoto]