23 September 2014
Vol 7, Issue 344

About The Cover

Cover image expansion

Online Cover This week features a Research Article that describes how fibroblast growth factor receptor 1 (FGFR1) attenuates endothelial-to-mesenchymal transition (EndMT) by inhibiting transforming growth factor–β (TGFβ) signaling in endothelial cells. The image shows that TGFβ signaling, as indicated by immunostaining for phosphorylated Smad2 (red), is minimal in endothelial cells (green) in a normal human artery. [Image: P.-Y. Chen/Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, and L. Qin/Department of Surgery, Yale University School of Medicine]