Research ArticleVASCULAR BIOLOGY
Localized TRPA1 channel Ca2+ signals stimulated by reactive oxygen species promote cerebral artery dilation
- Michelle N. Sullivan1,
- Albert L. Gonzales2,
- Paulo W. Pires3,
- Allison Bruhl1,
- M. Dennis Leo4,
- Wencheng Li1,
- Agathe Oulidi3,
- Frederick A. Boop5,
- Yumei Feng1,
- Jonathan H. Jaggar4,
- Donald G. Welsh6, and
- Scott Earley3,*
- 1Vascular Physiology Research Group, Department of Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA.
- 2Department of Pharmacology, University of Vermont School of Medicine, Burlington, VT 05405, USA.
- 3Department of Pharmacology, University of Nevada School of Medicine, Reno, NV 89557–0318, USA.
- 4Department of Physiology, University of Tennessee Health Science Center, Memphis, TN 38163, USA.
- 5Department of Neurosurgery, University of Tennessee Health Science Center, Memphis, TN 38163, USA.
- 6Department of Physiology and Pharmacology, University of Calgary, Calgary, Alberta T2N 4N1, Canada.
- ↵*Corresponding author. E-mail: searley{at}medicine.nevada.edu
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Science Signaling 06 Jan 2015:
Vol. 8, Issue 358, pp. ra2
DOI: 10.1126/scisignal.2005659