Research ArticleCell Biology
MAPK feedback encodes a switch and timer for tunable stress adaptation in yeast
- Justin G. English1,
- James P. Shellhammer1,
- Michael Malahe2,
- Patrick C. McCarter3,
- Timothy C. Elston1, and
- Henrik G. Dohlman1,4,*
- 1Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
- 2Department of Mathematics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
- 3Curriculum in Bioinformatics and Computational Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
- 4Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
- ↵*Corresponding author. E-mail: hdohlman{at}med.unc.edu
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Science Signaling 13 Jan 2015:
Vol. 8, Issue 359, pp. ra5
DOI: 10.1126/scisignal.2005774
Vol. 8, Issue 359, pp. ra5
DOI: 10.1126/scisignal.2005774
Justin G. English
1Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
James P. Shellhammer
1Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Michael Malahe
2Department of Mathematics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Patrick C. McCarter
3Curriculum in Bioinformatics and Computational Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Timothy C. Elston
1Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Henrik G. Dohlman
1Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
4Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.