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Research ArticlePhysiology
DDR2 (discoidin domain receptor 2) suppresses osteoclastogenesis and is a potential therapeutic target in osteoporosis
- Yan Zhang1,
- Jin Su2,
- Shufang Wu1,
- Yue Teng1,
- Zhanhai Yin3,
- Yan Guo4,
- Jing Li1,
- Kun Li5,
- Libo Yao2, and
- Xu Li1,*
- 1Center for Translational Medicine, the First Affiliated Hospital of Xi’an Jiaotong University College of Medicine, Xi’an, Shaanxi 710061, People’s Republic of China.
- 2Department of Biochemistry and Molecular Biology, the Fourth Military Medical University, Xi’an, Shaanxi 710032, People’s Republic of China.
- 3Department of Orthopaedics, the First Affiliated Hospital of Xi’an Jiaotong University College of Medicine, Xi’an, Shaanxi 710061, People’s Republic of China.
- 4Key Laboratory of Biomedical Information Engineering of Ministry of Education, and Institute of Molecular Genetics, School of Life Science and Technology, Xi’an Jiaotong University, Xi’an, Shaanxi 710049, People’s Republic of China.
- 5Clinical laboratory, ShanXi Mineral Hospital, Xi’an, Shaanxi 710014, People’s Republic of China.
- ↵*Corresponding author. E-mail: lixuxjtu{at}163.com
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Science Signaling 24 Mar 2015:
Vol. 8, Issue 369, pp. ra31
DOI: 10.1126/scisignal.2005835
Vol. 8, Issue 369, pp. ra31
DOI: 10.1126/scisignal.2005835
Yan Zhang
Center for Translational Medicine, the First Affiliated Hospital of Xi’an Jiaotong University College of Medicine, Xi’an, Shaanxi 710061, People’s Republic of China.
Jin Su
Department of Biochemistry and Molecular Biology, the Fourth Military Medical University, Xi’an, Shaanxi 710032, People’s Republic of China.
Shufang Wu
Center for Translational Medicine, the First Affiliated Hospital of Xi’an Jiaotong University College of Medicine, Xi’an, Shaanxi 710061, People’s Republic of China.
Yue Teng
Center for Translational Medicine, the First Affiliated Hospital of Xi’an Jiaotong University College of Medicine, Xi’an, Shaanxi 710061, People’s Republic of China.
Zhanhai Yin
Department of Orthopaedics, the First Affiliated Hospital of Xi’an Jiaotong University College of Medicine, Xi’an, Shaanxi 710061, People’s Republic of China.
Yan Guo
Key Laboratory of Biomedical Information Engineering of Ministry of Education, and Institute of Molecular Genetics, School of Life Science and Technology, Xi’an Jiaotong University, Xi’an, Shaanxi 710049, People’s Republic of China.
Jing Li
Center for Translational Medicine, the First Affiliated Hospital of Xi’an Jiaotong University College of Medicine, Xi’an, Shaanxi 710061, People’s Republic of China.
Kun Li
Clinical laboratory, ShanXi Mineral Hospital, Xi’an, Shaanxi 710014, People’s Republic of China.
Libo Yao
Department of Biochemistry and Molecular Biology, the Fourth Military Medical University, Xi’an, Shaanxi 710032, People’s Republic of China.
Xu Li
Center for Translational Medicine, the First Affiliated Hospital of Xi’an Jiaotong University College of Medicine, Xi’an, Shaanxi 710061, People’s Republic of China.
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