Research ArticleDNA damage Casein kinase 2 (CK2) phosphorylates the deubiquitylase OTUB1 at Ser16 to trigger its nuclear localization Lina Herhaus1, Ana B. Perez-Oliva1, Giorgio Cozza2, Robert Gourlay1, Simone Weidlich1, David G. Campbell1, Lorenzo A. Pinna2, and Gopal P. Sapkota1,*1MRC Protein Phosphorylation and Ubiquitylation Unit, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK.2Department of Biomedical Sciences and CNR Institute of Neurosciences, University of Padova, via Ugo Bassi 58/B, 35131 Padova, Italy.↵*Corresponding author. E-mail: g.sapkota{at}dundee.ac.uk See allHide authors and affiliations Science Signaling 14 Apr 2015:Vol. 8, Issue 372, pp. ra35DOI: 10.1126/scisignal.aaa0441 Lina Herhaus 1MRC Protein Phosphorylation and Ubiquitylation Unit, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK.Find this author on Google Scholar Find this author on PubMed Search for this author on this site Ana B. Perez-Oliva 1MRC Protein Phosphorylation and Ubiquitylation Unit, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK.Find this author on Google Scholar Find this author on PubMed Search for this author on this site Giorgio Cozza 2Department of Biomedical Sciences and CNR Institute of Neurosciences, University of Padova, via Ugo Bassi 58/B, 35131 Padova, Italy.Find this author on Google Scholar Find this author on PubMed Search for this author on this site Robert Gourlay 1MRC Protein Phosphorylation and Ubiquitylation Unit, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK.Find this author on Google Scholar Find this author on PubMed Search for this author on this site Simone Weidlich 1MRC Protein Phosphorylation and Ubiquitylation Unit, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK.Find this author on Google Scholar Find this author on PubMed Search for this author on this site David G. Campbell 1MRC Protein Phosphorylation and Ubiquitylation Unit, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK.Find this author on Google Scholar Find this author on PubMed Search for this author on this site Lorenzo A. Pinna 2Department of Biomedical Sciences and CNR Institute of Neurosciences, University of Padova, via Ugo Bassi 58/B, 35131 Padova, Italy.Find this author on Google Scholar Find this author on PubMed Search for this author on this site Gopal P. Sapkota 1MRC Protein Phosphorylation and Ubiquitylation Unit, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK.Find this author on Google Scholar Find this author on PubMed Search for this author on this site For correspondence: g.sapkota@dundee.ac.uk Article Figures & Data Info & Metrics eLetters PDF Article Information vol. 8 no. 372 ra35 DOI: https://doi.org/10.1126/scisignal.aaa0441 PubMed: 25872870 Published By: Science Signaling Print ISSN: 1945-0877 Online ISSN: 1937-9145 History: Received October 9, 2014Accepted March 17, 2015 . Copyright & Usage: Copyright © 2015, American Association for the Advancement of Science Author Information Altmetric Article usage Article lifetimeLast 6 monthsThis monthArticle usage: April 2015 to January 2021 AbstractFullPdf Apr 20153690257234 May 20152635561 Jun 20151573141 Jul 20151101644 Aug 201519629 Sep 20151013269 Oct 20152012199 Nov 2015133187 Dec 2015513196 Jan 20162921152 Feb 2016441611 Mar 20164321021 Apr 2016374210 May 20161201937 Jun 2016881556 Jul 2016662115 Aug 2016713087 Sep 2016622625 Oct 20168027711 Nov 2016613069 Dec 201641161 Jan 2017741425 Feb 2017572128 Mar 2017592787 Apr 2017332113 May 2017472616 Jun 2017372627 Jul 2017402091 Aug 2017401814 Sep 2017451468 Oct 2017372861 Nov 2017482471 Dec 2017192222 Jan 2018343145 Feb 2018541445 Mar 201860910 Apr 2018641311 May 20186269 Jun 201853610 Jul 20184195 Aug 20183041 Sep 20183350 Oct 201840131 Nov 201844352 Dec 20184083 Jan 201942107 Feb 20194133 Mar 201926123 Apr 20192782 May 20193590 Jun 201928108 Jul 20193073 Aug 20192391 Sep 201926116 Oct 20193186 Nov 201932124 Dec 20193841 Jan 202029133 Feb 202020164 Mar 202018104 Apr 20203352 May 20202492 Jun 20202681 Jul 202025103 Aug 202013103 Sep 202019130 Oct 202036165 Nov 20204284 Dec 202020147 Jan 20211192 View Full Text
Casein kinase 2 (CK2) phosphorylates the deubiquitylase OTUB1 at Ser16 to trigger its nuclear localization By Lina Herhaus, Ana B. Perez-Oliva, Giorgio Cozza, Robert Gourlay, Simone Weidlich, David G. Campbell, Lorenzo A. Pinna, Gopal P. Sapkota Science Signaling14 Apr 2015 : ra35 The kinase CK2 promotes the nuclear function of the deubiquitylase OTUB1 in DNA damage repair. Supplementary Materials
Casein kinase 2 (CK2) phosphorylates the deubiquitylase OTUB1 at Ser16 to trigger its nuclear localization By Lina Herhaus, Ana B. Perez-Oliva, Giorgio Cozza, Robert Gourlay, Simone Weidlich, David G. Campbell, Lorenzo A. Pinna, Gopal P. Sapkota Science Signaling14 Apr 2015 : ra35 The kinase CK2 promotes the nuclear function of the deubiquitylase OTUB1 in DNA damage repair. Supplementary Materials