12 May 2015
Vol 8, Issue 376

About The Cover

Cover image expansion

Online Cover This week features a Research Article that describes how increasing the activity of the transcription factor GATA-6 in injured blood vessels in mice prevents excessive proliferation of vascular smooth muscle cells and the formation of scar tissue called neointima, which narrows the lumen of blood vessels. The image shows a blood vessel in which neointima has formed between the endothelial cell layer lining the lumen and the internal elastic lamina (the dark brown wavy line) in response to injury. [Image: Yu Jin and Jun Yu/Yale University School of Medicine, New Haven, CT]