Research ArticleImmunology
CD4+ T cell–dependent and CD4+ T cell–independent cytokine-chemokine network changes in the immune responses of HIV-infected individuals
- Kelly B. Arnold1,*,
- Gregory L. Szeto1,2,3,4,*,
- Galit Alter2,
- Darrell J. Irvine1,2,3,4,5,†, and
- Douglas A. Lauffenburger1,†
- 1Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
- 2Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA.
- 3The David H. Koch Institute for Integrative Cancer Research, Cambridge, MA 02139, USA.
- 4Department of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
- 5Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
- ↵†Corresponding author. E-mail: djirvine{at}mit.edu (D.J.I.); lauffen{at}mit.edu (D.A.L.)
↵* These authors contributed equally to this work.
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Science Signaling 20 Oct 2015:
Vol. 8, Issue 399, pp. ra104
DOI: 10.1126/scisignal.aab0808
Vol. 8, Issue 399, pp. ra104
DOI: 10.1126/scisignal.aab0808
Kelly B. Arnold
1Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Gregory L. Szeto
1Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
2Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA.
3The David H. Koch Institute for Integrative Cancer Research, Cambridge, MA 02139, USA.
4Department of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Galit Alter
2Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA.
Darrell J. Irvine
1Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
2Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA.
3The David H. Koch Institute for Integrative Cancer Research, Cambridge, MA 02139, USA.
4Department of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
5Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Douglas A. Lauffenburger
1Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
