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Research ArticleVASCULAR BIOLOGY
Endothelial cells decode VEGF-mediated Ca2+ signaling patterns to produce distinct functional responses
- David P. Noren1,2,
- Wesley H. Chou3,
- Sung Hoon Lee4,
- Amina A. Qutub2,
- Aryeh Warmflash2,3,
- Daniel S. Wagner3,
- Aleksander S. Popel1,*, and
- Andre Levchenko4,*
- 1Department of Biomedical Engineering, Johns Hopkins University School of Medicine, 720 Rutland Avenue, Baltimore, MD 21205, USA.
- 2Department of Bioengineering, Rice University, 6100 Main Street, Houston, TX 77005, USA.
- 3Department of Biosciences, Rice University, Houston, TX 77005, USA.
- 4Yale Systems Biology Institute and Department of Biomedical Engineering, Yale University, 850 West Campus Drive, West Haven, CT 06516, USA.
- ↵*Corresponding author. E-mail: andre.levchenko{at}yale.edu (A.L.); apopel{at}jhu.edu (A.S.P.)
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Science Signaling 23 Feb 2016:
Vol. 9, Issue 416, pp. ra20
DOI: 10.1126/scisignal.aad3188
Vol. 9, Issue 416, pp. ra20
DOI: 10.1126/scisignal.aad3188
David P. Noren
1Department of Biomedical Engineering, Johns Hopkins University School of Medicine, 720 Rutland Avenue, Baltimore, MD 21205, USA.
2Department of Bioengineering, Rice University, 6100 Main Street, Houston, TX 77005, USA.
Wesley H. Chou
3Department of Biosciences, Rice University, Houston, TX 77005, USA.
Sung Hoon Lee
4Yale Systems Biology Institute and Department of Biomedical Engineering, Yale University, 850 West Campus Drive, West Haven, CT 06516, USA.
Amina A. Qutub
2Department of Bioengineering, Rice University, 6100 Main Street, Houston, TX 77005, USA.
Aryeh Warmflash
2Department of Bioengineering, Rice University, 6100 Main Street, Houston, TX 77005, USA.
3Department of Biosciences, Rice University, Houston, TX 77005, USA.
Daniel S. Wagner
3Department of Biosciences, Rice University, Houston, TX 77005, USA.
Aleksander S. Popel
1Department of Biomedical Engineering, Johns Hopkins University School of Medicine, 720 Rutland Avenue, Baltimore, MD 21205, USA.
Andre Levchenko
4Yale Systems Biology Institute and Department of Biomedical Engineering, Yale University, 850 West Campus Drive, West Haven, CT 06516, USA.
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