08 March 2016
Vol 9, Issue 418

About The Cover

Cover image expansion

Online Cover This week features a Focus Issue that highlights molecular insights into the cell-specific roles and regulation of the ORAI Ca2+ channel in cells of the immune system. The image shows the CAR (calcium-accumulating region) at the extracellular side of the ORAI channel. [Image: Shmuel Muallem, National Institutes of Health, National Institute of Dental and Craniofacial Research; structure provided by Rainer Schindl, Institute of Biophysics, Johannes Kepler University, Linz, Austria]