Article Information
vol. 9 no. 425 ra42
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History:
- Received September 7, 2015
- Accepted April 8, 2016
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Copyright © 2016, American Association for the Advancement of Science
Research ArticleVASCULAR BIOLOGY
Neuropilin-1 mediates vascular permeability independently of vascular endothelial growth factor receptor-2 activation
- Lise Roth1,2,
- Claudia Prahst1,*,
- Tina Ruckdeschel1,
- Soniya Savant1,†,
- Simone Weström1,‡,
- Alessandro Fantin3,
- Maria Riedel1,
- Mélanie Héroult1,§,
- Christiana Ruhrberg3, and
- Hellmut G. Augustin1,2,¶
- 1Division of Vascular Oncology and Metastasis, German Cancer Research Center (DKFZ-ZMBH Alliance), 69120 Heidelberg, Germany.
- 2Department of Vascular Biology and Tumor Angiogenesis (CBTM), Medical Faculty Mannheim, Heidelberg University, 68167 Mannheim, Germany.
- 3UCL Institute of Ophthalmology, University College London, EC1V 9EL London, UK.
- ↵¶Corresponding author. Email: augustin{at}angiogenese.de
↵* Present address: Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA.
↵† Present address: Department of Cell and Molecular Biology, Karolinska Institute, SE-171 Stockholm, Sweden.
↵‡ Present address: Department of Medical Sciences, Uppsala Universitet, 751 05 Uppsala, Sweden.
↵§ Present address: BAYER AG, Innovation Strategy Department, 51368 Leverkusen, Germany.
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Science Signaling 26 Apr 2016:
Vol. 9, Issue 425, pp. ra42
DOI: 10.1126/scisignal.aad3812
Vol. 9, Issue 425, pp. ra42
DOI: 10.1126/scisignal.aad3812
Lise Roth
Division of Vascular Oncology and Metastasis, German Cancer Research Center (DKFZ-ZMBH Alliance), 69120 Heidelberg, Germany.Department of Vascular Biology and Tumor Angiogenesis (CBTM), Medical Faculty Mannheim, Heidelberg University, 68167 Mannheim, Germany.
Claudia Prahst
Division of Vascular Oncology and Metastasis, German Cancer Research Center (DKFZ-ZMBH Alliance), 69120 Heidelberg, Germany.
Tina Ruckdeschel
Division of Vascular Oncology and Metastasis, German Cancer Research Center (DKFZ-ZMBH Alliance), 69120 Heidelberg, Germany.
Soniya Savant
Division of Vascular Oncology and Metastasis, German Cancer Research Center (DKFZ-ZMBH Alliance), 69120 Heidelberg, Germany.
Simone Weström
Division of Vascular Oncology and Metastasis, German Cancer Research Center (DKFZ-ZMBH Alliance), 69120 Heidelberg, Germany.
Alessandro Fantin
UCL Institute of Ophthalmology, University College London, EC1V 9EL London, UK.
Maria Riedel
Division of Vascular Oncology and Metastasis, German Cancer Research Center (DKFZ-ZMBH Alliance), 69120 Heidelberg, Germany.
Mélanie Héroult
Division of Vascular Oncology and Metastasis, German Cancer Research Center (DKFZ-ZMBH Alliance), 69120 Heidelberg, Germany.
Christiana Ruhrberg
UCL Institute of Ophthalmology, University College London, EC1V 9EL London, UK.
Hellmut G. Augustin
Division of Vascular Oncology and Metastasis, German Cancer Research Center (DKFZ-ZMBH Alliance), 69120 Heidelberg, Germany.Department of Vascular Biology and Tumor Angiogenesis (CBTM), Medical Faculty Mannheim, Heidelberg University, 68167 Mannheim, Germany.
