Research ArticleVASCULAR BIOLOGY
Neuropilin-1 mediates vascular permeability independently of vascular endothelial growth factor receptor-2 activation
- Lise Roth1,2,
- Claudia Prahst1,*,
- Tina Ruckdeschel1,
- Soniya Savant1,†,
- Simone Weström1,‡,
- Alessandro Fantin3,
- Maria Riedel1,
- Mélanie Héroult1,§,
- Christiana Ruhrberg3, and
- Hellmut G. Augustin1,2,¶
- 1Division of Vascular Oncology and Metastasis, German Cancer Research Center (DKFZ-ZMBH Alliance), 69120 Heidelberg, Germany.
- 2Department of Vascular Biology and Tumor Angiogenesis (CBTM), Medical Faculty Mannheim, Heidelberg University, 68167 Mannheim, Germany.
- 3UCL Institute of Ophthalmology, University College London, EC1V 9EL London, UK.
- ↵¶Corresponding author. Email: augustin{at}angiogenese.de
↵* Present address: Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA.
↵† Present address: Department of Cell and Molecular Biology, Karolinska Institute, SE-171 Stockholm, Sweden.
↵‡ Present address: Department of Medical Sciences, Uppsala Universitet, 751 05 Uppsala, Sweden.
↵§ Present address: BAYER AG, Innovation Strategy Department, 51368 Leverkusen, Germany.
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Science Signaling 26 Apr 2016:
Vol. 9, Issue 425, pp. ra42
DOI: 10.1126/scisignal.aad3812
