FIBROSIS
Teaming up against inflammation and fibrosis
Combined blockade of TSLP, IL-25, and IL-33 may be needed to treat some forms of progressive inflammation and fibrosis.
K. M. Vannella, T. R. Ramalingam, L. A. Borthwick, L. Barron, K. M. Hart, R. W. Thompson, K. N. Kindrachuk, A. W. Cheever, S. White, A. L. Budelsky, M. R. Comeau, D. E. Smith, T. A. Wynn, Combinatorial targeting of TSLP, IL-25, and IL-33 in type 2 cytokine–driven inflammation and fibrosis. Sci. Transl. Med. 8, 337ra65 (2016). [Abstract]
