Editors' ChoiceMEDICINE

Paper of note in Science Translational Medicine

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Science Signaling  10 May 2016:
Vol. 9, Issue 427, pp. ec112
DOI: 10.1126/scisignal.aag0549


Teaming up against inflammation and fibrosis

Combined blockade of TSLP, IL-25, and IL-33 may be needed to treat some forms of progressive inflammation and fibrosis.

K. M. Vannella, T. R. Ramalingam, L. A. Borthwick, L. Barron, K. M. Hart, R. W. Thompson, K. N. Kindrachuk, A. W. Cheever, S. White, A. L. Budelsky, M. R. Comeau, D. E. Smith, T. A. Wynn, Combinatorial targeting of TSLP, IL-25, and IL-33 in type 2 cytokine–driven inflammation and fibrosis. Sci. Transl. Med. 8, 337ra65 (2016). [Abstract]

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