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vol. 9 no. 430 ra55
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History:
- Received June 15, 2015
- Accepted May 13, 2016
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Copyright © 2016, American Association for the Advancement of Science
Research ArticlePharmacology
Identification of a small-molecule ligand that activates the neuropeptide receptor GPR171 and increases food intake
- Jonathan H. Wardman1,*,†,
- Ivone Gomes1,*,
- Erin N. Bobeck1,*,
- Jennifer A. Stockert1,
- Abhijeet Kapoor2,
- Paola Bisignano2,
- Achla Gupta1,
- Mihaly Mezei2,
- Sanjai Kumar3,
- Marta Filizola2, and
- Lakshmi A. Devi1,‡
- 1Department of Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
- 2Department of Structural and Chemical Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
- 3Department of Chemistry and Biochemistry, Queens College, Flushing, NY 11367, USA.
- ↵‡Corresponding author. Email: lakshmi.devi{at}mssm.edu
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Science Signaling 31 May 2016:
Vol. 9, Issue 430, pp. ra55
DOI: 10.1126/scisignal.aac8035
Vol. 9, Issue 430, pp. ra55
DOI: 10.1126/scisignal.aac8035
Jonathan H. Wardman
1Department of Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Ivone Gomes
1Department of Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Erin N. Bobeck
1Department of Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Jennifer A. Stockert
1Department of Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Abhijeet Kapoor
2Department of Structural and Chemical Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Paola Bisignano
2Department of Structural and Chemical Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Achla Gupta
1Department of Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Mihaly Mezei
2Department of Structural and Chemical Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Sanjai Kumar
3Department of Chemistry and Biochemistry, Queens College, Flushing, NY 11367, USA.
Marta Filizola
2Department of Structural and Chemical Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Lakshmi A. Devi
1Department of Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
