Research ArticleStem Cells
RhoA inhibits neural differentiation in murine stem cells through multiple mechanisms
- Junning Yang1,
- Chuanshen Wu2,*,
- Ioana Stefanescu1,
- Lars Jakobsson3,
- Inna Chervoneva4, and
- Arie Horowitz1,†
- 1Cardeza Foundation for Hematologic Research, Department of Medicine, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA 19107, USA.
- 2Department of Molecular Cardiology, Cleveland Clinic Foundation, Cleveland, OH 44195, USA.
- 3Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm 17177, Sweden.
- 4Division of Biostatistics, Department of Pharmacology and Experimental Therapeutics, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA 19107, USA.
- ↵†Corresponding author. Email: arie.horowitz{at}jefferson.edu
↵* Present address: Department of Psychiatry, Brookdale University Hospital and Medical Center, One Brookdale Plaza, Brooklyn, NY 11212, USA.
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Science Signaling 26 Jul 2016:
Vol. 9, Issue 438, pp. ra76
DOI: 10.1126/scisignal.aaf0791
Vol. 9, Issue 438, pp. ra76
DOI: 10.1126/scisignal.aaf0791
Junning Yang
1Cardeza Foundation for Hematologic Research, Department of Medicine, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA 19107, USA.
Chuanshen Wu
2Department of Molecular Cardiology, Cleveland Clinic Foundation, Cleveland, OH 44195, USA.
Ioana Stefanescu
1Cardeza Foundation for Hematologic Research, Department of Medicine, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA 19107, USA.
Lars Jakobsson
3Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm 17177, Sweden.
Inna Chervoneva
4Division of Biostatistics, Department of Pharmacology and Experimental Therapeutics, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA 19107, USA.
Arie Horowitz
1Cardeza Foundation for Hematologic Research, Department of Medicine, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA 19107, USA.
