TRANSPLANTATION
Make way for stem cells
Combining antibodies against c-Kit with CD47 blockade depletes endogenous hematopoietic stem cells and enables bone marrow transplantation without radiation or chemotherapeutics.
A. Chhabra, A. M. Ring, K. Weiskopf, P. J. Schnorr, S. Gordon, A. C. Le, H.-S. Kwon, N. G. Ring, J. Volkmer, P. Y. Ho, S. Tseng, I. L. Weissman, J. A. Shizuru, Hematopoietic stem cell transplantation in immunocompetent hosts without radiation or chemotherapy. Sci. Transl. Med. 8, 351ra105 (2016). [Abstract]
