Editors' ChoiceCancer

Paper of note in Science Translational Medicine

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Science Signaling  06 Sep 2016:
Vol. 9, Issue 444, pp. ec206
DOI: 10.1126/scisignal.aai9255


Showing ALL that resistance is futile

The combination of venetoclax and dasatinib is synergistically effective in treating Philadelphia chromosome–positive ALL.

J. T. Leonard, J. S. J. Rowley, C. A. Eide, E. Traer, B. Hayes-Lattin, M. Loriaux, S. E. Spurgeon, B. J. Druker, J. W. Tyner, B. H. Chang, Targeting BCL-2 and ABL/LYN in Philadelphia chromosome–positive acute lymphoblastic leukemia. Sci. Transl. Med. 8, 354ra114 (2016). [Abstract]

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