ASTHMA
Advanced analysis of asthma
The development of allergic asthma requires type 2 airway inflammation as well as increased sensitivity of airway epithelial cells and smooth muscle to inflammation.
J. L. Cho, M. F. Ling, D. C. Adams, L. Faustino, S. A. Islam, R. Afshar, J. W. Griffith, R. S. Harris, A. Ng, G. Radicioni, A. A. Ford, A. K. Han, R. Xavier, W. W. Kwok, R. Boucher, J. J. Moon, D. L. Hamilos, M. Kesimer, M. J. Suter, B. D. Medoff, A. D. Luster, Allergic asthma is distinguished by sensitivity of allergen-specific CD4+ T cells and airway structural cells to type 2 inflammation. Sci. Transl. Med. 8, 359ra132 (2016). [Abstract]
