CELL DEATH
DNA damage–activated nuclease identified
An endonuclease that functions in a disease-associated form of cell death is identified.
Y. Wang, R. An, G. K. Umanah, H. Park, K. Nambiar, S. M. Eacker, B. Kim, L. Bao, M. M. Harraz, C. Chang, R. Chen, J. E. Wang, T.-I. Kam, J. S. Jeong, Z. Xie, S. Neifert, J. Qian, S. A. Andrabi, S. Blackshaw, H. Zhu, H. Song, G.-l. Ming, V. L. Dawson, T. M. Dawson, A nuclease that mediates cell death induced by DNA damage and poly(ADP-ribose) polymerase-1. Science 353, aad6872 (2016). [Abstract]
E. Jonas, The MIFstep in parthanatos. Science 353, 36–37 (2016). [Abstract]
