CELL REPROGRAMMING
For cell reprogramming, context matters
Tissue damage and senescence provide critical signals for cellular reprogramming in vivo.
L. Mosteiro, C. Pantoja, N. Alcazar, R. M. Marión, D. Chondronasiou, M. Rovira, P. J. Fernandez-Marcos, M. Muñoz-Martin, C. Blanco-Aparicio, J. Pastor, G. Gómez-López, A. De Martino, M. A. Blasco, M. Abad, M. Serrano, Tissue damage and senescence provide critical signals for cellular reprogramming in vivo. Science 354, aaf4445 (2016). [Abstract]
AUTOPHAGY
Open Sesame!
The ATG conjugation systems are important for degradation of the inner autophagosomal membrane.
K. Tsuboyama, I. Koyama-Honda, Y. Sakamaki, M. Koike, H. Morishita, N. Mizushima, The ATG conjugation systems are important for degradation of the inner autophagosomal membrane. Science 354, 1036–1041 (2016). [Abstract]
B. Levine, Closing the loop. Science 354, 968–969 (2016). [Abstract]
BEHAVIORAL IMMUNOLOGY
Status alters immune function in macaques
Social status alters immune regulation and response to infection in macaques.
N. Snyder-Mackler, J. Sanz, J. N. Kohn, J. F. Brinkworth, S. Morrow, A. O. Shaver, J.-C. Grenier, R. Pique-Regi, Z. P. Johnson, M. E. Wilson, L. B. Barreiro, J. Tung, Social status alters immune regulation and response to infection in macaques. Science 354, 1041–1045 (2016). [Abstract]
R. M. Sapolsky, Proinflammatory primates. Science 354, 967–968 (2016). [Abstract]
