SYNTHETIC BIOLOGY
Engineering cells to regulate glucose
A synthetic circuit provides effective glucose regulation by designer mammalian cells in diabetic mice.
M. Xie, H. Ye, H. Wang, G. Charpin-El Hamri, C. Lormeau, P. Saxena, J. Stelling, M. Fussenegger, β-cell–mimetic designer cells provide closed-loop glycemic control. Science 354, 1296–1301 (2016). [Abstract]
