PARKINSON’S DISEASE
A mitochondrial target for slowing Parkinson’s disease
Mitochondrial pyruvate carrier may be a therapeutic target in Parkinson’s disease.
A. Ghosh, T. Tyson, S. George, E. N. Hildebrandt, J. A. Steiner, Z. Madaj, E. Schulz, E. Machiela, W. G. McDonald, M. L. Escobar Galvis, J. H. Kordower, J. M. Van Raamsdonk, J. R. Colca, P. Brundin, Mitochondrial pyruvate carrier regulates autophagy, inflammation, and neurodegeneration in experimental models of Parkinson’s disease. Sci. Transl. Med. 8, 368ra174 (2016). [Abstract]
