Supplementary Materials

Supplementary Materials for:

Estrogen Reduces Lipid Content in the Liver Exclusively from Membrane Receptor Signaling

Ali Pedram, Mahnaz Razandi, Fiona O'Mahony, Harry Harvey, Brian J. Harvey, Ellis R. Levin*

*Corresponding author. E-mail: ellis.levin@va.gov

This PDF file includes:

  • Fig. S1. Experimental design of in vivo studies.
  • Fig. S2. PPT modulates selective gene expression comparably in wild-type and MOER mouse livers.
  • Fig. S3. AMPK and ERK mediate the PPT inhibition of insulin-induced abundance of Srebf1 and Hmgcr1.
  • Fig. S4. PPT-induced inhibition of Srebf1 processing is a posttranscriptional event.
  • Fig. S5. Summary of ER signaling from the membrane.
  • Table S1. Validation of gene modulation by PPT from qPCR using hepatic RNA.
  • Table S2. Primer sequences.

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Citation: A. Pedram, M. Razandi, F. O'Mahony, H. Harvey, B. J. Harvey, E. R. Levin, Estrogen Reduces Lipid Content in the Liver Exclusively from Membrane Receptor Signaling. Sci. Signal. 6, ra36 (2013).

© 2013 American Association for the Advancement of Science