Supplementary Materials for:

Heteromeric MT₁/MT₂ Melatonin Receptors Modulate Photoreceptor Function

Kenkichi Baba, Abla Benleulmi-Chaachoua, Anne-Sophie Journé, Maud Kamal, Jean-Luc Guillaume, Sébastien Dussaud, Florence Gbahou, Katia Yettou, Cuimei Liu, Susana Contreras-Alcantara, Ralf Jockers,* Gianluca Tosini*

*Corresponding author. E-mail: gtosini@msm.edu (G.T.); ralf.jockers@inserm.fr (R.J.)

This PDF file includes:

• Fig. S1. Flag and Myc immunoreactivity in the photoreceptors Flag-MT₁ and Myc- MT₂ mice.
• Fig. S2. Competition binding of 2-[¹²⁵I]iodomelatonin on membranes of HEK293 cells expressing mouse MT₁ and MT₂.
• Fig. S3. The effect of luzindole and 4P-PDOT on the ERG.
• Fig. S4. Functional characterization of the MT₂-P95L mutant in transfected HEK293T cells.
• Fig. S5. The effect of different signaling pathway stimulators and inhibitors on the amplitude of the a-wave at 7 ms.
• Fig. S6. Inhibition of melatonin-induced IP production by 4P-PDOT.

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Citation: K. Baba, A. Benleulmi-Chaachoua, A.-S. Journé, M. Kamal, J.-L. Guillaume, S. Dussaud, F. Gbahou, K. Yettou, C. Liu, S. Contreras-Alcantara, R. Jockers, G. Tosini, Heteromeric MT₁/MT₂ Melatonin Receptors Modulate Photoreceptor Function. Sci. Signal. 6, ra89 (2013).

© 2013 American Association for the Advancement of Science