Supplementary Materials

Supplementary Materials for:

Distinct Signaling Roles of Ceramide Species in Yeast Revealed Through Systematic Perturbation and Systems Biology Analyses

David J. Montefusco, Lujia Chen, Nabil Matmati, Songjian Lu, Benjamin Newcomb, Gregory F. Cooper, Yusuf A. Hannun,* Xinghua Lu*

*Corresponding author. E-mail: yusuf.hannun@stonybrookmedicine.edu (Y.A.H.); xinghua@pitt.edu (X.L.)

This PDF file includes:

  • Fig. S1. The effect of myristate on the lipidomic profile, including the effect on sphingoids.
  • Fig. S2. Validation of lipid-specific growth phenotypes in triplicate.
  • Table S2. Microarray data heat stress.
  • Table S7. All treatments tested for fatty acid–specific growth defects.
  • Table S8. Yeast strains used in this study.
  • Legends for tables S1, S3 to S6

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Other Supplementary Material for this manuscript includes the following:

  • Table S1. Lipidomics data under all combinations of treatments (xlxs).
  • Table S3. Microarray data under all combinations of treatments (xlxs).
  • Table S4. List of lipid-gene pairs showing significant association measured by MIC (xlxs).
  • Table S5. List of lipid-gene pairs showing significant Pearson correlations (xlxs).
  • Table S6. List of lipid-gene pairs showing significant associations measured using Bayesian regression (xlxs).

[Tables S1 to S6 ]


Citation: D. J. Montefusco, L. Chen, N. Matmati, S. Lu, B. Newcomb, G. F. Cooper, Y. A. Hannun, X. Lu, Distinct Signaling Roles of Ceramide Species in Yeast Revealed Through Systematic Perturbation and Systems Biology Analyses. Sci. Signal. 6, rs14 (2013).

© 2013 American Association for the Advancement of Science