Supplementary Materials
ROMO1 Is an Essential Redox-Dependent Regulator of Mitochondrial Dynamics
Matthew Norton, Andy Cheuk-Him Ng, Stephen Baird, Ariane Dumoulin, Timothy Shutt, Nancy Mah, Miguel A. Andrade-Navarro, Heidi M. McBride, Robert A. Screaton*
*Corresponding author. E-mail: rob@arc.cheo.ca
This PDF file includes:
- Fig. S1. The high-throughput mitochondrial morphology screen identifies ROMO1 as a regulator of mitochondrial fusion.
- Fig. S2. Full-length multiple-sequence alignment of ROMO1 with orthologs.
- Fig. S3. Reversible oxidation of ROMO1 and rescue of mitochondrial morphology with siRNA-resistant ROMO1 constructs.
- Fig. S4. ROMO1 associates with, but does not affect, integrity of MINOS.
- Fig. S5. Normal cellular ATP content and mitochondrial membrane potential in ROMO1 knockdown cells.
- Fig. S6. Effect of ROMO1 status on OPA1 isoform balance.
- References (66, 67)
Technical Details
Format: Adobe Acrobat PDF
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Citation: M. Norton, A. C.-H. Ng, S. Baird, A. Dumoulin, T. Shutt, N. Mah, M. A. Andrade-Navarro, H. M. McBride, R. A. Screaton, ROMO1 Is an Essential Redox-Dependent Regulator of Mitochondrial Dynamics. Sci. Signal. 7, ra10 (2014).