Supplementary Materials

Supplementary Materials for:

REDD1 enhances protein phosphatase 2A–mediated dephosphorylation of Akt to repress mTORC1 signaling

Michael D. Dennis, Catherine S. Coleman, Arthur Berg, Leonard S. Jefferson, Scot R. Kimball*

*Corresponding author. E-mail: skimball@psu.edu

This PDF file includes:

  • Fig. S1. Effect of REDD1 on the interaction of 14-3-3 protein with TSC2.
  • Fig. S2. REDD1 promotes the dephosphorylation of Akt on Thr308.
  • Fig. S3. Regulation of the phosphorylation of Akt on Thr308 and the TSC2-TBC complex by REDD1.

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Citation: M. D. Dennis, C. S. Coleman, A. Berg, L. S. Jefferson, S. R. Kimball, REDD1 enhances protein phosphatase 2A–mediated dephosphorylation of Akt to repress mTORC1 signaling. Sci. Signal. 7, ra68 (2014).

© 2014 American Association for the Advancement of Science