Supplementary Materials

Supplementary Materials for:

Peripheral pain is enhanced by insulin-like growth factor 1 through a G protein–mediated stimulation of T-type calcium channels

Yuan Zhang, Wenjuan Qin, Zhiyuan Qian, Xingjun Liu, Hua Wang, Shan Gong, Yan-Gang Sun,* Terrance P. Snutch, Xinghong Jiang, Jin Tao*

*Corresponding author. E-mail: taoj{at}suda.edu.cn (J.T.); yangang.sun{at}ion.ac.cn (Y.-G.S.)

This PDF file includes:

  • Fig. S1. Cell surface abundance of IR and IGF-1R in DRGs.
  • Fig. S2. Knockdown of IGF-R1 in DRGs.
  • Fig. S3. Colocalization of IGF-1R with CaV3.2 in mouse DRGs.
  • Fig. S4. Knockdown of PKCα in DRGs.
  • Fig. S5. Uptake of siRNA in DRGs.
  • Table S1. Membrane properties of small DRG neurons induced by IGF-1 in mice.

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Citation: Y. Zhang, W. Qin, Z. Qian, X. Liu, H. Wang, S. Gong, Y.-G. Sun, T. P. Snutch, X. Jiang, J. Tao, Peripheral pain is enhanced by insulin-like growth factor 1 through a G protein–mediated stimulation of T-type calcium channels. Sci. Signal. 7, ra94 (2014).

© 2014 American Association for the Advancement of Science