Supplementary Materials

Supplementary Materials for:

Neuregulin 1–activated ERBB4 interacts with YAP to induce Hippo pathway target genes and promote cell migration

Jonathan W. Haskins, Don X. Nguyen, David F. Stern*

*Corresponding author. E-mail: df.stern{at}yale.edu

This PDF file includes:

  • Fig. S1. DOX-inducible expression of ERBB4.
  • Fig. S2. Impact of YAP S127A substitution on ERBB4 induction of CTGF.
  • Fig. S3. ERBB4-TEAD1 interaction in the nucleus.
  • Fig. S4. Impact of erlotinib on EGFR phosphorylation induced by EGF or NRG1.
  • Fig. S5. NRG1 regulates YAP independently of mevalonate and TGF-β pathways.
  • Fig. S6. NRG1 does not induce migration in MCF10A cells.

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Citation: J. W. Haskins, D. X. Nguyen, D. F. Stern, Neuregulin 1–activated ERBB4 interacts with YAP to induce Hippo pathway target genes and promote cell migration. Sci. Signal. 7, ra116 (2014).

© 2014 American Association for the Advancement of Science