Supplementary Materials

Supplementary Materials for:

Shedding of the tumor necrosis factor (TNF) receptor from the surface of hepatocytes during sepsis limits inflammation through cGMP signaling

Meihong Deng, Patricia A. Loughran, Liyong Zhang, Melanie J. Scott, Timothy R. Billiar*

*Corresponding author. E-mail: billiartr{at}upmc.edu

This PDF file includes:

  • Fig. S1. The kinetics of TNFR1 and TNF release after CLP.
  • Fig. S2. Analysis of plasma IL-1β concentrations at 8 hours after CLP.
  • Fig. S3. The responses to LPS of hepatocytes from Alb-Cre mice are similar to those of hepatocytes from wild-type mice.
  • Fig. S4. The responses to LPS of cells from Lyz-Cre mice are similar to those of cells from wild-type mice.

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Citation: M. Deng, P. A. Loughran, L. Zhang, M. J. Scott, T. R. Billiar, Shedding of the tumor necrosis factor (TNF) receptor from the surface of hepatocytes during sepsis limits inflammation through cGMP signaling. Sci. Signal. 8, ra11 (2015).

© 2014 American Association for the Advancement of Science