Supplementary Materials

Supplementary Materials for:

The G protein α subunit variant XLαs promotes inositol 1,4,5- trisphosphate signaling and mediates the renal actions of parathyroid hormone in vivo

Qing He, Yan Zhu, Braden A. Corbin, Antonius Plagge, Murat Bastepe*

*Corresponding author. E-mail: bastepe{at}helix.mgh.harvard.edu

This PDF file includes:

  • Fig. S1. XLαs is located in the kidney at early postnatal stages, and XLKO mice do not have defects in renal structure.
  • Fig. S2. The abundances of Npt2a protein and Slc20a2 mRNA are similar between P2 wild-type and XLKO mice.
  • Fig. S3. Increased renal Gαs abundance in P2 XLKO kidneys.
  • Fig. S4. The abundances of PKCβII, PKCθ, phosphorylated ERK1/2, and phosphorylated substrates of PKA are not decreased in the proximal tubules of P2 XLKO mice.
  • Table. S1. Sequences of the primer pairs used in qRT-PCR assays.

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Citation: Q. He, Y. Zhu, B. A. Corbin, A. Plagge, M. Bastepe, The G protein α subunit variant XLαs promotes inositol 1,4,5-trisphosphate signaling and mediates the renal actions of parathyroid hormone in vivo. Sci. Signal. 8, ra84 (2015).

© 2015 American Association for the Advancement of Science