Supplementary Materials

Supplementary Materials for:

The early synthesis of p35 and activation of CDK5 in LPS-stimulated macrophages suppresses interleukin-10 production

Yi Rang Na, Daun Jung, Gyo Jeong Gu, Ah Ram Jang, Yoo-Hun Suh, Seung Hyeok Seok*

*Corresponding author. E-mail: lamseok{at}snu.ac.kr

This PDF file includes:

  • Fig. S1. Analysis of Cdk5r1 mRNA and p35 protein abundance in macrophages from various sources.
  • Legend for fig. S2
  • Fig. S3. Immune cell composition in the lamina propria of mice with colitis.
  • Fig. S4. Analysis of p35 abundance in Kupffer cells from LPS-treated septic mice.
  • Table S1. List of genes with increased expression in BMDMs from p35 KO mice whose products are enriched in downstream targets of NF-κB and MAPK signaling by network analysis.

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Other Supplementary Material for this manuscript includes the following:

  • Fig. S2 (.pdf format). Pathway analysis of microarray data from LPS-stimulated mouse macrophages.

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Citation: Y. R. Na, D. Jung, G. J. Gu, A. R. Jang, Y.-H. Suh, S. H. Seok, The early synthesis of p35 and activation of CDK5 in LPS-stimulated macrophages suppresses interleukin-10 production. Sci. Signal. 8, ra121 (2015).

© 2015 American Association for the Advancement of Science