Supplementary Materials
Inhibition of the kinase WNK1/HSN2 ameliorates neuropathic pain by restoring GABA inhibition
Kristopher T. Kahle,* Jean-François Schmouth, Valérie Lavastre, Alban Latremoliere, Jinwei Zhang, Nick Andrews, Takao Omura, Janet Laganière, Daniel Rochefort, Pascale Hince, Geneviève Castonguay, Rébecca Gaudet, Josiane C. S. Mapplebeck, Susana G. Sotocinal, JingJing Duan, Catherine Ward, Arjun R. Khanna, Jeffrey S. Mogil, Patrick A. Dion, Clifford J. Woolf, Perrine Inquimbert, Guy A. Rouleau*
*Corresponding author. E-mail: guy.rouleau{at}mcgill.ca (G.A.R.); kristopher.kahle{at}yale.edu (K.T.K.)
This PDF file includes:
- Fig. S1. Strategy for making and validation of the Wnk1/Hsn2 knockout mice.
- Table S1. Nerve size quantification summary of Wnk1+/+ and Wnk1ΔHsn2/ΔHsn2 mice.
- Table S2. PCR primers used.
Technical Details
Format: Adobe Acrobat PDF
Size: 741 KB
Citation: K. T. Kahle, J.-F. Schmouth, V. Lavastre, A. Latremoliere, J. Zhang, N. Andrews, T. Omura, J. Laganière, D. Rochefort, P. Hince, G. Castonguay, R. Gaudet, J. C. S. Mapplebeck, S. G. Sotocinal, J. Duan, C.Ward, A. R. Khanna, J. S. Mogil, P. A. Dion, C. J.Woolf, P. Inquimbert, G. A. Rouleau, Inhibition of the kinase WNK1/HSN2 ameliorates neuropathic pain by restoring GABA inhibition. Sci. Signal. 9, ra32 (2016).