Supplementary Materials

Supplementary Materials for:

Transforming growth factor–β and Notch ligands act as opposing environmental cues in regulating the plasticity of type 3 innate lymphoid cells

Charlotte Viant, Lucille C. Rankin, Mathilde J. H. Girard-Madoux, Cyril Seillet, Wei Shi, Mark J. Smyth, Laurent Bartholin, Thierry Walzer, Nicholas D. Huntington, Eric Vivier,* Gabrielle T. Belz*

*Corresponding author. Email: vivier{at}ciml.univ-mrs.fr (E.V.); belz{at}wehi.edu.au (G.T.B.)

This PDF file includes:

  • Fig. S1. Characterization of ILCs in the small intestine of R26RFP/RFP Ncr1-iCre mice
    at steady state.
  • Fig. S2. Ncr1 FM of NKp46+ and NKp46 hematopoietic cells.
  • Fig. S3. Analyses of ILC3 populations in the colon and cecum in the presence of a
    constitutively active form of TGF-βRI.
  • Fig. S4. Analyses of small intestinal ILC3 populations expressing a constitutively active form of TGF-βRI in vivo.
  • Fig. S5. In vitro analyses of the differentiation of small intestinal ILC3 populations expressing a constitutively active form of TGF-βRI.
  • Fig. S6. Small intestinal ILCs of TgfbRIIfl/fl Ncr1-iCre mice.

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Citation: C. Viant, L. C. Rankin, M. J. H. Girard-Madoux, C. Seillet, W. Shi, M. J. Smyth, L. Bartholin, T. Walzer, N. D. Huntington, E. Vivier, G. T. Belz, Transforming growth factor–β and Notch ligands act as opposing environmental cues in regulating the plasticity of type 3 innate lymphoid cells. Sci. Signal. 9, ra46 (2016).

© 2016 American Association for the Advancement of Science