Supplementary Materials

Supplementary Materials for:

The transcription factor FOXF1 promotes prostate cancer by stimulating the mitogen-activated protein kinase ERK5

Logan Fulford, David Milewski, Vladimir Ustiyan, Navin Ravishankar, Yuqi Cai, Tien Le, Sreeharsha Masineni, Susan Kasper, Bruce Aronow, Vladimir V. Kalinichenko, Tanya V. Kalin*

*Corresponding author. Email: tatiana.kalin{at}cchmc.org

This PDF file includes:

  • Fig. S1. Overexpression of Foxf1 increases cellular proliferation, invasion, and migration of PCa tumor cells in culture.
  • Fig. S2. Overexpression of Foxf1 in orthotopic xenografts induces EMT.
  • Fig. S3. Overexpression of Foxf1 induces activation of the MAPK pathway in TRAMP orthotopic tumors.
  • Fig. S4. Depletion of FOXF1 reduces the growth of human PCa xenografts.
  • Fig. S5. Pharmacological inhibition of ERK5 in FoxF1-OE PCa cells decreases tumor cell proliferation, invasion, and migration in culture.
  • Fig. S6. FOXF1 expression is increased in a subset of human prostate cancers.
  • Table S1. TaqMan probes.

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Citation: L. Fulford, D. Milewski, V. Ustiyan, N. Ravishankar, Y. Cai, T. Le, S. Masineni, S. Kasper, B. Aronow, V. V. Kalinichenko, T. V. Kalin, The transcription factor FOXF1 promotes prostate cancer by stimulating the mitogen-activated protein kinase ERK5. Sci. Signal. 9, ra48 (2016).

© 2016 American Association for the Advancement of Science