Supplementary Materials

Supplementary Materials for:

The endothelial adaptor molecule TSAd is required for VEGF-induced angiogenic sprouting through junctional c-Src activation

Emma J. Gordon,* Daisuke Fukuhara, Simone Weström, Narendra Padhan, Elisabet O. Sjöström, Laurens van Meeteren, Liqun He, Fabrizio Orsenigo, Elisabetta Dejana, Katie Bentley, Anne Spurkland, Lena Claesson-Welsh*

*Corresponding author. Email: emma.gordon{at}igp.uu.se (E.J.G.); lena.welsh{at}igp.uu.se (L.C.-W.)

This PDF file includes:

  • Fig. S1. TSAd is not required for developmental retinal angiogenesis.
  • Fig. S2. Generation of TSAd conditional knockout mice.
  • Fig. S3. TSAd-deficient tracheas have normal lymphatic vessel morphology.
  • Fig. S4. Expression profiles of Tsad and associated genes.
  • Fig. S5. TSAd-deficient cells express Dll4.
  • Fig. S6. The SH2 and C-terminal domains of TSAd are necessary for sprouting.

[Download PDF]

Technical Details

Format: Adobe Acrobat PDF

Size: 833 KB


Citation: E. J. Gordon, D. Fukuhara, S. Weström, N. Padhan, E. O. Sjöström, L. van Meeteren, L. He, F. Orsenigo, E. Dejana, K. Bentley, A. Spurkland, L. Claesson-Welsh, The endothelial adaptor molecule TSAd is required for VEGF-induced angiogenic sprouting through junctional c-Src activation. Sci. Signal. 9, ra72 (2016).

© 2016 American Association for the Advancement of Science