Supplementary Materials

Supplementary Materials for:

Distinct microenvironmental cues stimulate divergent TLR4-mediated signaling pathways in macrophages

Anna M. Piccinini, Lorena Zuliani-Alvarez, Jenny M. P. Lim, Kim S. Midwood*

*Corresponding author. Email: kim.midwood{at}kennedy.ox.ac.uk

This PDF file includes:

  • Fig. S1. FBG-mediated activation of macrophages is not inhibited by polymyxin B.
  • Fig. S2. Validation of phosphoprotein enrichment.
  • Fig. S3. Signaling pathway analysis of macrophages activated with FBG or LPS.
  • Fig. S4. Comparison of LPS- and FBG-stimulated MAPK signaling in macrophages.
  • Fig. S5. Analysis of LPS- and FBG-stimulated collagen synthesis by macrophages.
  • Fig. S6. Analysis of the amount of pro-MMP1 protein in macrophages stimulated with LPS or FBG.

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Citation: A. M. Piccinini, L. Zuliani-Alvarez, J. M. P. Lim, K. S. Midwood, Distinct microenvironmental cues stimulate divergent TLR4-mediated signaling pathways in macrophages. Sci. Signal. 9, ra86 (2016).

© 2016 American Association for the Advancement of Science