Supplementary Materials

Supplementary Materials for:

AML suppresses hematopoiesis by releasing exosomes that contain microRNAs targeting c-MYB

Noah I. Hornick, Ben Doron, Sherif Abdelhamed, Jianya Huan, Christina A. Harrington, Rongkun Shen, Xiaolu A. Cambronne, Santhosh Chakkaramakkil Verghese, Peter Kurre*

*Corresponding author. Email: kurrepe{at}ohsu.edu

This PDF file includes:

  • Fig. S1. In vivo imaging correlates with chimerism.
  • Fig. S2. Intrafemoral injections of exosomes decrease expression of hematopoietic genes.
  • Fig. S3. Intravenous injections of exosomes decrease expression of hematopoietic genes.
  • Fig. S4. miR-155 knockdown in HL-60 cells shows no decrease in viability or proliferation.
  • Fig. S5. Exosome size profile is unaltered in miR-155 knockdown HL-60 cells.
  • Table S1. The top transcripts identified by the miR-155 RISC-trap assay.
  • Table S2. Primer sequences.

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Citation: N. I. Hornick, B. Doron, S. Abdelhamed, J. Huan, C. A. Harrington, R. Shen, X. A. Cambronne, S. Chakkaramakkil Verghese, P. Kurre, AML suppresses hematopoiesis by releasing exosomes that contain microRNAs targeting c-MYB. Sci. Signal. 9, ra88 (2016).

© 2016 American Association for the Advancement of Science