Supplementary Materials

Supplementary Materials for:

The receptor tyrosine kinase AXL mediates nuclear translocation of the epidermal growth factor receptor

Toni M. Brand, Mari Iida, Kelsey L. Corrigan, Cara M. Braverman, John P. Coan, Bailey G. Flanigan, Andrew P. Stein, Ravi Salgia, Jana Rolff, Randall J. Kimple, Deric L. Wheeler*

*Corresponding author. Email: dlwheeler{at}wisc.edu

This PDF file includes:

  • Fig. S1. Validation of EGFR primary antibody specificity for confocal IF microscopy.
  • Fig. S2. AXL promotes nEGFR abundance in CtxR clones.
  • Fig. S3. AXL activates the SFKs YES and LYN.
  • Fig. S4. AXL promotes nuclear trafficking of EGFR in HNSCC cell lines that are intrinsically resistant to cetuximab.
  • Fig. S5. AXL stimulates EGFR-HER3 interaction.

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Citation: T. M. Brand, M. Iida, K. L. Corrigan, C. M. Braverman, J. P. Coan, B. G. Flanigan, A. P. Stein, R. Salgia, J. Rolff, R. J. Kimple, D. L. Wheeler, The receptor tyrosine kinase AXL mediates nuclear translocation of the epidermal growth factor receptor. Sci. Signal. 10, eaag1064 (2017).

© 2017 American Association for the Advancement of Science