Supplementary Materials

Supplementary Materials for:

Signaling by two-component system noncognate partners promotes intrinsic tolerance to polymyxin B in uropathogenic Escherichia coli

Kirsten R. Guckes, Erin J. Breland, Ellisa W. Zhang, Sarah C. Hanks, Navleen K. Gill, Holly M. S. Algood, Jonathan E. Schmitz, Charles W. Stratton, Maria Hadjifrangiskou*

*Corresponding author. Email: maria.hadjifrangiskou{at}vanderbilt.edu

This PDF file includes:

  • Fig. S1. QseC activity is not enhanced in the presence of epinephrine.
  • Fig. S2. The qseBC transcriptional surge is specific to ferric iron.
  • Fig. S3. PMB tolerance after ferric iron preconditioning varies between clinical urinary isolates.
  • Table S1. QseB and QseC protein sequence identity among E. coli strains and other enteric bacteria.
  • Table S2. Bacterial strains.
  • Table S3. Plasmids.
  • Table S4. Primers and probes.

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Citation: K. R. Guckes, E. J. Breland, E. W. Zhang, S. C. Hanks, N. K. Gill, H. M. S. Algood, J. E. Schmitz, C. W. Stratton, M. Hadjifrangiskou, Signaling by two-component system noncognate partners promotes intrinsic tolerance to polymyxin B in uropathogenic Escherichia coli. Sci. Signal. 10, eaag1775 (2017).

© 2017 American Association for the Advancement of Science