Supplementary Materials

Supplementary Materials for:

The lysine deacetylase Sirtuin 1 modulates the localization and function of the Notch1 receptor in regulatory T cells

Nimi Marcel, Lakshmi R. Perumalsamy, Sanjay K. Shukla, Apurva Sarin*

*Corresponding author. Email: sarina{at}ncbs.res.in

This PDF file includes:

  • Fig. S1. Inhibition of Sirt1 with CHIC-35 affects NIC localization in Treg cells.
  • Fig. S2. Knockdown of Sirt1 affects the localization of NIC.
  • Fig. S3. Loss of Sirt1 inhibits the anti-apoptotic function of NIC in response to multiple stimuli.
  • Fig. S4. NIC4KR is resistant to modification by Sirt1.

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Citation: N. Marcel, L. R. Perumalsamy, S. K. Shukla, A. Sarin, The lysine deacetylase Sirtuin 1 modulates the localization and function of the Notch1 receptor in regulatory T cells. Sci. Signal. 10, eaah4679 (2017).

© 2017 American Association for the Advancement of Science